The older will serve the younger
Paul quotes God's word to Rebekah that the older son would serve the younger.
Not only that, but Rebecca’s children were conceived by one man, our father Isaac. Yet before the twins were born or had done anything good or bad, in order that God’s plan of election might stand, not by works but by Him who calls, she was told, “The older will serve the younger.”
Genesis 25:23 speaks of two nations in Rebekah's womb and says the older will serve the younger. Romans 9:10-12 says these words were spoken before the twins were born.